Isao Matsumoto Selected Research

Sialadenitis

9/2020	Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjögren's syndrome.
5/2015	The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome.
1/2015	M3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis.
1/2015	A crucial role of RORγt in the development of spontaneous Sialadenitis-like Sjögren's syndrome.
6/2014	The role of M3 muscarinic acetylcholine receptor reactive T cells in Sjögren's syndrome: a critical review.
5/2013	The crucial roles of IFN-γ in the development of M3 muscarinic acetylcholine receptor induced Sjögren's syndrome-like sialadenitis.
9/2012	Pathogenic role of anti-M3 muscarinic acetylcholine receptor immune response in Sjögren's syndrome.
12/2010	Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjögren's syndrome-like sialoadenitis.
7/2010	Functional role of M3 muscarinic acetylcholine receptor (M3R) reactive T cells and anti-M3R autoantibodies in patients with Sjögren's syndrome.

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Isao Matsumoto Research Topics

Disease

54	Rheumatoid Arthritis 02/2022 - 08/2002
39	Arthritis (Polyarthritis) 07/2021 - 04/2002
25	Neoplasms (Cancer) 01/2022 - 01/2003
19	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2021 - 04/2004
10	Autoimmune Diseases (Autoimmune Disease) 03/2021 - 04/2002
10	Immunoglobulin G4-Related Disease 01/2021 - 07/2012
9	Sialadenitis 09/2020 - 07/2010
9	Lung Neoplasms (Lung Cancer) 01/2020 - 05/2004
7	Inflammation (Inflammations) 01/2021 - 01/2009
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2019 - 08/2004
7	Experimental Arthritis 10/2018 - 06/2006
6	Fibrosis (Cirrhosis) 01/2021 - 07/2012
6	Lymphatic Metastasis 03/2017 - 08/2004
5	Osteoarthritis 10/2018 - 06/2004
5	Neoplasm Metastasis (Metastasis) 05/2012 - 08/2004
5	Necrosis 04/2009 - 03/2003
4	Dermatomyositis (Dermatopolymyositis) 01/2022 - 01/2006
4	Connective Tissue Diseases (Connective Tissue Disease) 05/2021 - 03/2013
4	Interstitial Lung Diseases (Interstitial Lung Disease) 06/2019 - 01/2006
4	Carcinoma (Carcinomatosis) 03/2014 - 05/2003
3	Myositis (Idiopathic Inflammatory Myopathies) 04/2022 - 07/2020
3	Malignant Mesothelioma 10/2020 - 01/2014
3	Synovitis 12/2012 - 09/2005
2	Amyopathic dermatomyositis 01/2021 - 07/2018
2	Pleurisy (Pleuritis) 10/2020 - 04/2018
2	Aortitis 10/2020 - 01/2009
2	Polymyositis 07/2020 - 01/2006
2	Psoriatic Arthritis 03/2020 - 04/2003
2	Fever (Fevers) 04/2018 - 01/2007
2	Hemorrhage 12/2017 - 04/2009

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 04/2022 - 01/2009
20	AntibodiesIBA 07/2021 - 04/2002
20	Peptides (Polypeptides)IBA 07/2021 - 01/2006
16	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 03/2020 - 04/2002
14	AutoantibodiesIBA 04/2022 - 08/2002
14	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2014 - 06/2004
13	Interleukin-6 (Interleukin 6)IBA 07/2021 - 01/2008
12	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2007
12	LigandsIBA 09/2020 - 01/2006
11	Interleukin-17 (Interleukin 17)IBA 09/2020 - 01/2008
9	CytokinesIBA 01/2016 - 01/2008
9	EnzymesIBA 08/2015 - 04/2002
8	Immunoglobulin G (IgG)IBA 10/2020 - 09/2005
7	Immunoglobulins (Immunoglobulin)IBA 04/2021 - 04/2002
7	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 09/2020 - 12/2010
7	Biological ProductsIBA 06/2019 - 04/2006
7	IsomerasesIBA 04/2012 - 08/2002
6	Abatacept (Orencia)FDA Link 02/2022 - 11/2014
6	Prednisolone (Predate)FDA LinkGeneric 05/2021 - 01/2004
6	Infliximab (Remicade)FDA Link 04/2020 - 07/2007
6	Messenger RNA (mRNA)IBA 01/2020 - 06/2004
6	Cyclosporine (Ciclosporin)FDA LinkGeneric 09/2018 - 01/2007
6	tocilizumab (atlizumab)FDA Link 04/2018 - 01/2007
6	AntigensIBA 06/2014 - 06/2006
5	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 06/2007
5	SteroidsIBA 07/2018 - 01/2004
5	Collagen Type II (Type II Collagen)IBA 10/2014 - 01/2006
4	beta-cyclodextrin tetradecasulfate (CTDS)IBA 05/2021 - 03/2013
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2021 - 01/2012
4	Anti-Citrullinated Protein AntibodiesIBA 03/2020 - 08/2015
4	InterleukinsIBA 12/2016 - 01/2008
4	Methotrexate (Mexate)FDA LinkGeneric 07/2015 - 01/2009
4	Vascular Endothelial Growth Factor CIBA 08/2013 - 08/2004
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2013 - 08/2004
4	Monoclonal AntibodiesIBA 12/2012 - 01/2008
4	TristetraprolinIBA 01/2008 - 06/2004
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2018
3	Therapeutic UsesIBA 01/2021 - 01/2008
3	HLA-DRB1 Chains (HLA DRB1)IBA 07/2020 - 01/2006
3	AutoantigensIBA 03/2020 - 10/2004
3	Tyrosine Kinase InhibitorsIBA 01/2019 - 11/2009
3	acetyl 4-aminosalicylic acidIBA 01/2017 - 08/2015
3	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 05/2015 - 01/2008
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2015 - 01/2006
3	Immunosuppressive Agents (Immunosuppressants)IBA 01/2012 - 01/2007
3	thiamine triphosphorate (TTP)IBA 01/2008 - 06/2004
3	Morphine (MS Contin)FDA LinkGeneric 03/2007 - 03/2003
3	Complementary DNA (cDNA)IBA 08/2006 - 06/2004
3	Codeine (Codeine Phosphate)FDA LinkGeneric 05/2003 - 03/2003
2	nuclear matrix protein 2IBA 01/2022 - 01/2021
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 11/2021 - 12/2017
2	CC ChemokinesIBA 07/2020 - 01/2020
2	HLA Antigens (Human Leukocyte Antigens)IBA 07/2020 - 01/2014
2	C-Reactive ProteinIBA 04/2020 - 01/2007
2	cyclic citrullinated peptideIBA 03/2020 - 01/2017
2	Tumor Necrosis Factor InhibitorsIBA 03/2020 - 07/2013
2	Interleukin-10 (Interleukin 10)IBA 01/2020 - 07/2012
2	osimertinibIBA 01/2020 - 01/2019
2	LactoferrinIBA 01/2020 - 10/2014
2	arginine deiminaseIBA 11/2019 - 08/2015
2	Protein-Arginine DeiminasesIBA 11/2019 - 05/2016
2	Antirheumatic Agents (DMARD)IBA 06/2019 - 01/2016
2	Biomarkers (Surrogate Marker)IBA 10/2018 - 01/2014
2	Paclitaxel (Taxol)FDA LinkGeneric 08/2018 - 03/2017

Therapy/Procedure

16	Therapeutics 03/2021 - 08/2002
5	Oral Administration 09/2020 - 01/2014
5	Drug Therapy (Chemotherapy) 06/2020 - 01/2003
3	Radiotherapy 01/2020 - 05/2012
2	Plasma Exchange 12/2020 - 07/2018
2	Lymph Node Excision (Lymph Node Dissection) 12/2017 - 09/2005